PTEN Inhibits Cell Proliferation, Promotes Cell Apoptosis, and Induces Cell Cycle Arrest via Downregulating the PI3K/AKT/hTERT Pathway in Lung Adenocarcinoma A549 Cells

PTEN plays an essential role in tumorigenesis and both its mutation and inactivation can influence proliferation, apoptosis, and cell cycle progression in tumor cells. However, the precise role of PTEN in lung cancer cells has not been well studied. To address this, we have generated lung adenocarci...

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Dettagli Bibliografici
Pubblicato in:Biomed Res Int
Autori principali: Lu, Xiao-Xiao, Cao, Lan-Yu, Chen, Xi, Xiao, Jian, Zou, Yong, Chen, Qiong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2016
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086351/
https://ncbi.nlm.nih.gov/pubmed/27822469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2476842
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