Antisense oligonucleotide targeting at the initiator of hTERT arrests growth of hepatoma cells

AIM: To evaluate the inhibitory effect of antisense phosphorothioate oligonucleotide (asON) complementary to the initiator of human telomerase catalytic subunit (hTERT) on the growth of hepatoma cells. METHODS: The as-hTERT was synthesized by using a DNA synthesizer. HepG2.2.15 cells were treated wi...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Liu, Su-Xia, Sun, Wen-Sheng, Cao, Ying-Lin, Ma, Chun-Hong, Han, Li-Hui, Zhang, Li-Ning, Wang, Zhen-Guang, Zhu, Fa-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2004
Assuntos:
Liver Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724927/
https://ncbi.nlm.nih.gov/pubmed/14760759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i3.366
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