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Combination of telomerase antisense oligonucleotides simultaneously targeting hTR and hTERT produces synergism of inhibition of telomerase activity and growth in human colon cancer cell line

AIM: To investigate synergism of inhibition of telomerase activity and proliferation of human colon cancer cells by combination of telomerase antisense oligonucleotides (ASODNs) simultaneously targeting human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) in vitro. METHODS:...

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Publicado en:World J Gastroenterol
Main Authors: Fu, Xiao-Hua, Zhang, Jian-Song, Zhang, Na, Zhang, Yang-De
Formato: Artigo
Idioma:Inglês
Publicado: Baishideng Publishing Group Inc 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250584/
https://ncbi.nlm.nih.gov/pubmed/15682468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i6.785
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