Combination of telomerase antisense oligonucleotides simultaneously targeting hTR and hTERT produces synergism of inhibition of telomerase activity and growth in human colon cancer cell line

AIM: To investigate synergism of inhibition of telomerase activity and proliferation of human colon cancer cells by combination of telomerase antisense oligonucleotides (ASODNs) simultaneously targeting human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) in vitro. METHODS:...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Fu, Xiao-Hua, Zhang, Jian-Song, Zhang, Na, Zhang, Yang-De
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2005
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250584/
https://ncbi.nlm.nih.gov/pubmed/15682468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i6.785
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