PTEN Inhibits Cell Proliferation, Promotes Cell Apoptosis, and Induces Cell Cycle Arrest via Downregulating the PI3K/AKT/hTERT Pathway in Lung Adenocarcinoma A549 Cells

PTEN plays an essential role in tumorigenesis and both its mutation and inactivation can influence proliferation, apoptosis, and cell cycle progression in tumor cells. However, the precise role of PTEN in lung cancer cells has not been well studied. To address this, we have generated lung adenocarci...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Lu, Xiao-Xiao, Cao, Lan-Yu, Chen, Xi, Xiao, Jian, Zou, Yong, Chen, Qiong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086351/
https://ncbi.nlm.nih.gov/pubmed/27822469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2476842
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