Cyclic AMP efflux inhibitors as potential therapeutic agents for leukemia

Apoptotic evasion is a hallmark of cancer. We propose that some cancers may evade cell death by regulating 3′-5′-cyclic adenosine monophosphate (cAMP), which is associated with pro-apoptotic signaling. We hypothesize that leukemic cells possess mechanisms that efflux cAMP from the cytoplasm, thus pr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Perez, Dominique R., Smagley, Yelena, Garcia, Matthew, Carter, Mark B., Evangelisti, Annette, Matlawska-Wasowska, Ksenia, Winter, Stuart S., Sklar, Larry A., Chigaev, Alexandre
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085131/
https://ncbi.nlm.nih.gov/pubmed/27129155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8986
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge