Phosphodiesterase Type 5 Inhibition Reduces Albuminuria in Subjects with Overt Diabetic Nephropathy

Diabetic nephropathy (DN) is the leading cause of ESRD worldwide. Reduced bioavailability or uncoupling of nitric oxide in the kidney, leading to decreased intracellular levels of the nitric oxide pathway effector molecule cyclic guanosine monophosphate (cGMP), has been implicated in the progression...

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Bibliografski detalji
Izdano u:J Am Soc Nephrol
Glavni autori: Scheele, Wim, Diamond, Susan, Gale, Jeremy, Clerin, Valerie, Tamimi, Nihad, Le, Vu, Walley, Rosalind, Grover-Páez, Fernando, Perros-Huguet, Christelle, Rolph, Timothy, El Nahas, Meguid
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2016
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084877/
https://ncbi.nlm.nih.gov/pubmed/27113485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015050473
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https://ncbi.nlm.nih.gov/pmc/articles/PMC5084877/
https://ncbi.nlm.nih.gov/pubmed/27113485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015050473