Effect of PF-04634817, an Oral CCR2/5 Chemokine Receptor Antagonist, on Albuminuria in Adults with Overt Diabetic Nephropathy

INTRODUCTION: Inflammatory cell recruitment, which is potentially mediated by the monocyte chemoattractant protein 1/C-C chemokine receptor type 2 (CCR2) system and by C-C chemokine receptor type 5 (CCR5) activity, may play a role in the development and progression of diabetic nephropathy. PF-046348...

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Detalhes bibliográficos
Publicado no:Kidney Int Rep
Main Authors: Gale, Jeremy D., Gilbert, Steven, Blumenthal, Samuel, Elliott, Tom, Pergola, Pablo E., Goteti, Kosalaram, Scheele, Wim, Perros-Huguet, Christelle
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224665/
https://ncbi.nlm.nih.gov/pubmed/30450458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ekir.2018.07.010
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