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Phosphodiesterase Type 5 Inhibition Reduces Albuminuria in Subjects with Overt Diabetic Nephropathy

Diabetic nephropathy (DN) is the leading cause of ESRD worldwide. Reduced bioavailability or uncoupling of nitric oxide in the kidney, leading to decreased intracellular levels of the nitric oxide pathway effector molecule cyclic guanosine monophosphate (cGMP), has been implicated in the progression...

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Dades bibliogràfiques
Publicat a:J Am Soc Nephrol
Autors principals: Scheele, Wim, Diamond, Susan, Gale, Jeremy, Clerin, Valerie, Tamimi, Nihad, Le, Vu, Walley, Rosalind, Grover-Páez, Fernando, Perros-Huguet, Christelle, Rolph, Timothy, El Nahas, Meguid
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084877/
https://ncbi.nlm.nih.gov/pubmed/27113485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015050473
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