Phosphodiesterase Type 5 Inhibition Reduces Albuminuria in Subjects with Overt Diabetic Nephropathy

Diabetic nephropathy (DN) is the leading cause of ESRD worldwide. Reduced bioavailability or uncoupling of nitric oxide in the kidney, leading to decreased intracellular levels of the nitric oxide pathway effector molecule cyclic guanosine monophosphate (cGMP), has been implicated in the progression...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Am Soc Nephrol
Prif Awduron: Scheele, Wim, Diamond, Susan, Gale, Jeremy, Clerin, Valerie, Tamimi, Nihad, Le, Vu, Walley, Rosalind, Grover-Páez, Fernando, Perros-Huguet, Christelle, Rolph, Timothy, El Nahas, Meguid
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Nephrology 2016
Pynciau:
Clinical Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084877/
https://ncbi.nlm.nih.gov/pubmed/27113485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015050473
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