Phosphodiesterase Type 5 Inhibition Reduces Albuminuria in Subjects with Overt Diabetic Nephropathy

Diabetic nephropathy (DN) is the leading cause of ESRD worldwide. Reduced bioavailability or uncoupling of nitric oxide in the kidney, leading to decreased intracellular levels of the nitric oxide pathway effector molecule cyclic guanosine monophosphate (cGMP), has been implicated in the progression...

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Udgivet i:J Am Soc Nephrol
Main Authors: Scheele, Wim, Diamond, Susan, Gale, Jeremy, Clerin, Valerie, Tamimi, Nihad, Le, Vu, Walley, Rosalind, Grover-Páez, Fernando, Perros-Huguet, Christelle, Rolph, Timothy, El Nahas, Meguid
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2016
Fag:
Clinical Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084877/
https://ncbi.nlm.nih.gov/pubmed/27113485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015050473
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