Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.

Eitemau Tebyg

• SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation
  gan: Matsuda, Morihiro, et al.
  Cyhoeddwyd: (2001)
• Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.
  gan: Shimano, H, et al.
  Cyhoeddwyd: (1996)
• SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
  gan: Horton, Jay D., et al.
  Cyhoeddwyd: (2002)
• Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.
  gan: Horton, J D, et al.
  Cyhoeddwyd: (1998)
• Cholesterol feeding reduces nuclear forms of sterol regulatory element binding proteins in hamster liver
  gan: Shimomura, Iichiro, et al.
  Cyhoeddwyd: (1997)