Llwytho...

Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.

The synthesis of cholesterol and its uptake from plasma LDL are regulated by two membrane-bound transcription factors, designated sterol regulatory element binding protein-1 and -2 (SREBP-1 and SREBP-2). Here, we used the technique of homologous recombination to generate mice with disruptions in the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shimano, H, Shimomura, I, Hammer, R E, Herz, J, Goldstein, J L, Brown, M S, Horton, J D
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1997
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC508404/
https://ncbi.nlm.nih.gov/pubmed/9329978
Tagiau: Ychwanegu Tag
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