Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.

Ítems similars

• Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.
  per: Shimano, H, et al.
  Publicat: (1997)
• Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.
  per: Horton, J D, et al.
  Publicat: (1998)
• SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
  per: Horton, Jay D., et al.
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• Blunted feedback suppression of SREBP processing by dietary cholesterol in transgenic mice expressing sterol-resistant SCAP(D443N).
  per: Korn, B S, et al.
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  per: Matsuda, Morihiro, et al.
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