Regulation of the gp80 and gp130 subunits of the IL-6 receptor by sex steroids in the murine bone marrow.

Both estrogen and androgen exert their antiosteoporotic effects, at least in part, by inhibiting IL-6 production, thereby suppressing osteoclastogenesis. Several observations, however, suggest that besides increased IL-6 production, sensitivity of the osteoclastogenic process to this cytokine is alt...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Lin, S C, Yamate, T, Taguchi, Y, Borba, V Z, Girasole, G, O'Brien, C A, Bellido, T, Abe, E, Manolagas, S C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508387/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9329961/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119729
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