Regulation of the gp80 and gp130 subunits of the IL-6 receptor by sex steroids in the murine bone marrow.

Both estrogen and androgen exert their antiosteoporotic effects, at least in part, by inhibiting IL-6 production, thereby suppressing osteoclastogenesis. Several observations, however, suggest that besides increased IL-6 production, sensitivity of the osteoclastogenic process to this cytokine is alt...

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Bibliografiske detaljer
Main Authors: Lin, S C, Yamate, T, Taguchi, Y, Borba, V Z, Girasole, G, O'Brien, C A, Bellido, T, Abe, E, Manolagas, S C
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC508387/
https://ncbi.nlm.nih.gov/pubmed/9329961
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