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A system to study aneuploidy in vivo

Aneuploidy, an imbalanced chromosome number, is associated with both cancer and developmental disorders such as Down syndrome (DS). To determine how aneuploidy affects cellular and organismal physiology, we have developed a system to evaluate aneuploid cell fitness in vivo. By transplanting hematopo...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Symp Quant Biol
Main Authors: Pfau, Sarah J., Amon, Angelika
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082706/
https://ncbi.nlm.nih.gov/pubmed/26936868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/sqb.2015.80.027193
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