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New Insights into the Troubles of Aneuploidy

Deviation from a balanced genome by either gain or loss of entire chromosomes is generally poorly tolerated in all eukaryotic systems studied to date. Errors in mitotic or meiotic cell division lead to aneuploidy, which places a burden of additional or insufficient gene products from the mis-segrega...

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Detalhes bibliográficos
Main Authors: Siegel, Jake J., Amon, Angelika
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919630/
https://ncbi.nlm.nih.gov/pubmed/22804579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-cellbio-101011-155807
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