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Human aneuploidy: mechanisms and new insights into an age-old problem

Trisomic and monosomic (aneuploid) embryos account for at least 10% of human pregnancies and, for women nearing the end of their reproductive lifespan, the incidence may exceed 50%. The errors that lead to aneuploidy almost always occur in the oocyte but, despite intensive investigation, the underly...

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Detalhes bibliográficos
Main Authors: Nagaoka, So I., Hassold, Terry J., Hunt, Patricia A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551553/
https://ncbi.nlm.nih.gov/pubmed/22705668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3245
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