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Inefficient crossover maturation underlies elevated aneuploidy in human female meiosis
Meiosis is the cellular program that underlies gamete formation. For this program, crossovers between homologous chromosomes play an essential mechanical role to ensure regular segregation. We present a detailed study of crossover formation in human male and female meiosis, enabled by modeling analy...
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| Pubblicato in: | Cell |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5408880/ https://ncbi.nlm.nih.gov/pubmed/28262352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.02.002 |
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