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Inefficient crossover maturation underlies elevated aneuploidy in human female meiosis

Meiosis is the cellular program that underlies gamete formation. For this program, crossovers between homologous chromosomes play an essential mechanical role to ensure regular segregation. We present a detailed study of crossover formation in human male and female meiosis, enabled by modeling analy...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell
Päätekijät: Wang, Shunxin, Hassold, Terry, Hunt, Patricia, White, Martin A., Zickler, Denise, Kleckner, Nancy, Zhang, Liangran
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408880/
https://ncbi.nlm.nih.gov/pubmed/28262352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.02.002
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