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Chromosomal instability and aneuploidy in cancer: from yeast to man

Aneuploidy is frequently associated with disease and developmental abnormalities. It is also a key characteristic of cancer. Several model systems have been developed to study the role of chromosomal instability and aneuploidy in tumorigenesis. The results are surprisingly complex, with the conditio...

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Detalhes bibliográficos
Main Authors: Pfau, Sarah J, Amon, Angelika
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367249/
https://ncbi.nlm.nih.gov/pubmed/22614003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.65
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