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Aneuploidy causes proteotoxic stress in yeast
Gains or losses of entire chromosomes lead to aneuploidy, a condition tolerated poorly in all eukaryotes analyzed to date. How aneuploidy affects organismal and cellular physiology is poorly understood. We found that aneuploid budding yeast cells are under proteotoxic stress. Aneuploid strains are p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3533075/ https://ncbi.nlm.nih.gov/pubmed/23222101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.207407.112 |
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