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Aneuploidy Drives Genomic Instability in Yeast
Aneuploidy decreases cellular fitness, yet it is also associated with cancer, a disease of enhanced proliferative capacity. To investigate one mechanism by which aneuploidy could contribute to tumorigenesis, we examined the effects of aneuploidy on genomic stability. We analyzed 13 budding yeast str...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3278960/ https://ncbi.nlm.nih.gov/pubmed/21852501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1206412 |
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