Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints.

Lignende værker

• VDIPEN, a metalloproteinase-generated neoepitope, is induced and immunolocalized in articular cartilage during inflammatory arthritis.
  af: Singer, I I, et al.
  Udgivet: (1995)
• The role of aggrecan in normal and osteoarthritic cartilage
  af: Roughley, Peter J, et al.
  Udgivet: (2014)
• Aggrecan is degraded by matrix metalloproteinases in human arthritis. Evidence that matrix metalloproteinase and aggrecanase activities can be independent.
  af: Fosang, A J, et al.
  Udgivet: (1996)
• Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro.
  af: Little, C B, et al.
  Udgivet: (1999)
• Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repair
  af: Little, Christopher B., et al.
  Udgivet: (2007)