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Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro.

The importance of aggrecanase versus matrix metalloproteinase (MMP) enzymic activities in the degradation of aggrecan in normal and osteoarthritic (OA) articular cartilage in vitro was studied in order to further our understanding of the potential role of these two enzyme activities in aggrecan cata...

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Autors principals: Little, C B, Flannery, C R, Hughes, C E, Mort, J S, Roughley, P J, Dent, C, Caterson, B
Format: Artigo
Idioma:Inglês
Publicat: 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220614/
https://ncbi.nlm.nih.gov/pubmed/10548534
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