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Hypoxia increases genome-wide bivalent epigenetic marking by specific gain of H3K27me3
BACKGROUND: Trimethylation at histone H3 lysine 4 (H3K4me3) and lysine 27 (H3K27me3) controls gene activity during development and differentiation. Whether H3K4me3 and H3K27me3 changes dynamically in response to altered microenvironmental conditions, including low-oxygen conditions commonly present...
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| 出版年: | Epigenetics Chromatin |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5080723/ https://ncbi.nlm.nih.gov/pubmed/27800026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-016-0086-0 |
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