Quantitative analysis of ChIP-seq data uncovers dynamic and sustained H3K4me3 and H3K27me3 modulation in cancer cells under hypoxia

BACKGROUND: A comprehensive assessment of the epigenetic dynamics in cancer cells is the key to understanding the molecular mechanisms underlying cancer and to improving cancer diagnostics, prognostics and treatment. By combining genome-wide ChIP-seq epigenomics and microarray transcriptomics, we st...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Epigenetics Chromatin
Prif Awduron: Adriaens, Michiel E., Prickaerts, Peggy, Chan-Seng-Yue, Michelle, van den Beucken, Twan, Dahlmans, Vivian E. H., Eijssen, Lars M., Beck, Timothy, Wouters, Bradly G., Voncken, Jan Willem, Evelo, Chris T. A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2016
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5090954/
https://ncbi.nlm.nih.gov/pubmed/27822313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-016-0090-4
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