MK3 Modulation Affects BMI1-Dependent and Independent Cell Cycle Check-Points

Although the MK3 gene was originally found deleted in some cancers, it is highly expressed in others. The relevance of MK3 for oncogenesis is currently not clear. We recently reported that MK3 controls ERK activity via a negative feedback mechanism. This prompted us to investigate a potential role f...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Prickaerts, Peggy, Niessen, Hanneke E. C., Dahlmans, Vivian E. H., Spaapen, Frank, Salvaing, Juliette, Vanhove, Jolien, Geijselaers, Claudia, Bartels, Stefanie J. J., Partouns, Iris, Neumann, Dietbert, Speel, Ernst-Jan, Takihara, Yoshihiro, Wouters, Bradly G., Voncken, Jan Willem
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390245/
https://ncbi.nlm.nih.gov/pubmed/25853770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118840
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