MK3 Modulation Affects BMI1-Dependent and Independent Cell Cycle Check-Points

Although the MK3 gene was originally found deleted in some cancers, it is highly expressed in others. The relevance of MK3 for oncogenesis is currently not clear. We recently reported that MK3 controls ERK activity via a negative feedback mechanism. This prompted us to investigate a potential role f...

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Publicat a:PLoS One
Autors principals: Prickaerts, Peggy, Niessen, Hanneke E. C., Dahlmans, Vivian E. H., Spaapen, Frank, Salvaing, Juliette, Vanhove, Jolien, Geijselaers, Claudia, Bartels, Stefanie J. J., Partouns, Iris, Neumann, Dietbert, Speel, Ernst-Jan, Takihara, Yoshihiro, Wouters, Bradly G., Voncken, Jan Willem
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390245/
https://ncbi.nlm.nih.gov/pubmed/25853770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118840
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