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Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers
Interaction mapping is a powerful strategy to elucidate the biological function of protein assemblies and their regulators. Here, we report the generation of a quantitative interaction network, directly linking 14 human proteins to the AAA+ ATPase p97, an essential hexameric protein with multiple ce...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5080433/ https://ncbi.nlm.nih.gov/pubmed/27762274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13047 |
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