Quantitative GTPase Affinity Purification Identifies Rho Family Protein Interaction Partners

Although Rho GTPases are essential molecular switches involved in many cellular processes, an unbiased experimental comparison of their interaction partners was not yet performed. Here, we develop quantitative GTPase affinity purification (qGAP) to systematically identify interaction partners of six...

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Publicat a:Mol Cell Proteomics
Autors principals: Paul, Florian, Zauber, Henrik, von Berg, Laura, Rocks, Oliver, Daumke, Oliver, Selbach, Matthias
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217783/
https://ncbi.nlm.nih.gov/pubmed/27852748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.061531
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