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Quantitative GTPase Affinity Purification Identifies Rho Family Protein Interaction Partners

Although Rho GTPases are essential molecular switches involved in many cellular processes, an unbiased experimental comparison of their interaction partners was not yet performed. Here, we develop quantitative GTPase affinity purification (qGAP) to systematically identify interaction partners of six...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Proteomics
Hauptverfasser: Paul, Florian, Zauber, Henrik, von Berg, Laura, Rocks, Oliver, Daumke, Oliver, Selbach, Matthias
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217783/
https://ncbi.nlm.nih.gov/pubmed/27852748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.061531
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