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The UBX Protein SAKS1 Negatively Regulates Endoplasmic Reticulum-associated Degradation and p97-dependent Degradation

Endoplasmic reticulum-associated degradation (ERAD) is an essential quality control process whereby misfolded proteins are exported from the endoplasmic reticulum and degraded by the proteasome in the cytosol. The ATPase p97 acts as an essential component of this process by providing the force neede...

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Detalhes bibliográficos
Main Authors: LaLonde, David P., Bretscher, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039385/
https://ncbi.nlm.nih.gov/pubmed/21135095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.158030
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