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Ubx4 Modulates Cdc48 Activity and Influences Degradation of Misfolded Proteins of the Endoplasmic Reticulum

Misfolded proteins of the secretory pathway are recognized in the endoplasmic reticulum (ER), retrotranslocated into the cytoplasm, and degraded by the ubiquitin-proteasome system. Right after retrotranslocation and polyubiquitination, they are extracted from the cytosolic side of the ER membrane th...

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Autori principali: Alberts, Sven M., Sonntag, Caroline, Schäfer, Antje, Wolf, Dieter H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713509/
https://ncbi.nlm.nih.gov/pubmed/19359248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809282200
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