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Structural insights into oligomerization and mitochondrial remodelling of dynamin 1-like protein

Dynamin 1-like protein (DNM1L) mediates fission of mitochondria and peroxisomes, and dysfunction of DNM1L has been implicated in several neurological disorders. To study the molecular basis of mitochondrial remodelling, we determined the crystal structure of DNM1L that is comprised of a G domain, a...

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Autori principali: Fröhlich, Chris, Grabiger, Stefan, Schwefel, David, Faelber, Katja, Rosenbaum, Eva, Mears, Jason, Rocks, Oliver, Daumke, Oliver
Natura: Artigo
Lingua:Inglês
Pubblicazione: European Molecular Biology Organization 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642683/
https://ncbi.nlm.nih.gov/pubmed/23584531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.74
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