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Structural insights into oligomerization and mitochondrial remodelling of dynamin 1-like protein

Dynamin 1-like protein (DNM1L) mediates fission of mitochondria and peroxisomes, and dysfunction of DNM1L has been implicated in several neurological disorders. To study the molecular basis of mitochondrial remodelling, we determined the crystal structure of DNM1L that is comprised of a G domain, a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fröhlich, Chris, Grabiger, Stefan, Schwefel, David, Faelber, Katja, Rosenbaum, Eva, Mears, Jason, Rocks, Oliver, Daumke, Oliver
Format: Artigo
Sprache:Inglês
Veröffentlicht: European Molecular Biology Organization 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642683/
https://ncbi.nlm.nih.gov/pubmed/23584531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.74
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