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Dynamin-like MxA GTPase: Structural Insights into Oligomerization and Implications for Antiviral Activity

The interferon-inducible MxA GTPase is a key mediator of cell-autonomous innate immunity against a broad range of viruses such as influenza and bunyaviruses. MxA shares a similar domain structure with the dynamin superfamily of mechanochemical enzymes, including an N-terminal GTPase domain, a centra...

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Detalhes bibliográficos
Main Authors: Haller, Otto, Gao, Song, von der Malsburg, Alexander, Daumke, Oliver, Kochs, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937866/
https://ncbi.nlm.nih.gov/pubmed/20538602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R110.145839
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