Structure of the MxA stalk elucidates the assembly of ring-like units of an antiviral module

The dynamin-like MxA GTP ase (Myxovirus resistance protein 1) mediates cellular resistance against a wide range of viruses. MxA is composed of an amino-terminal G domain, a middle domain and a carboxy-terminal GTPase effector domain. We recently determined the structure of the middle domain and GTPa...

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Main Authors: Daumke, Oliver, Gao, Song, von der Malsburg, Alexander, Haller, Otto, Kochs, Georg
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109478/
https://ncbi.nlm.nih.gov/pubmed/21686120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.1.1.12989
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