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Structural Requirements for the Antiviral Activity of the Human MxA Protein against Thogoto and Influenza A Virus

The interferon-induced dynamin-like MxA protein has broad antiviral activity against many viruses, including orthomyxoviruses such as influenza A and Thogoto virus and bunyaviruses such as La Crosse virus. MxA consists of an N-terminal globular GTPase domain, a connecting bundle signaling element, a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Patzina, Corinna, Haller, Otto, Kochs, Georg
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937669/
https://ncbi.nlm.nih.gov/pubmed/24448803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.543892
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