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Structural Requirements for the Antiviral Activity of the Human MxA Protein against Thogoto and Influenza A Virus
The interferon-induced dynamin-like MxA protein has broad antiviral activity against many viruses, including orthomyxoviruses such as influenza A and Thogoto virus and bunyaviruses such as La Crosse virus. MxA consists of an N-terminal globular GTPase domain, a connecting bundle signaling element, a...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937669/ https://ncbi.nlm.nih.gov/pubmed/24448803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.543892 |
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