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Antivirally active MxA protein sequesters La Crosse virus nucleocapsid protein into perinuclear complexes

Bunyaviruses replicate in the cytoplasm of infected cells. New viral particles are formed by budding of nucleocapsids into the Golgi apparatus. We have previously shown that the IFN-induced human MxA protein inhibits bunyavirus replication by an unknown mechanism. Here we demonstrate that MxA binds...

詳細記述

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書誌詳細
主要な著者: Kochs, Georg, Janzen, Christian, Hohenberg, Heinz, Haller, Otto
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC122488/
https://ncbi.nlm.nih.gov/pubmed/11880649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052430399
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