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Antivirally active MxA protein sequesters La Crosse virus nucleocapsid protein into perinuclear complexes

Bunyaviruses replicate in the cytoplasm of infected cells. New viral particles are formed by budding of nucleocapsids into the Golgi apparatus. We have previously shown that the IFN-induced human MxA protein inhibits bunyavirus replication by an unknown mechanism. Here we demonstrate that MxA binds...

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Detaylı Bibliyografya
Asıl Yazarlar: Kochs, Georg, Janzen, Christian, Hohenberg, Heinz, Haller, Otto
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC122488/
https://ncbi.nlm.nih.gov/pubmed/11880649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052430399
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