Antivirally active MxA protein sequesters La Crosse virus nucleocapsid protein into perinuclear complexes

Bunyaviruses replicate in the cytoplasm of infected cells. New viral particles are formed by budding of nucleocapsids into the Golgi apparatus. We have previously shown that the IFN-induced human MxA protein inhibits bunyavirus replication by an unknown mechanism. Here we demonstrate that MxA binds...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Kochs, Georg, Janzen, Christian, Hohenberg, Heinz, Haller, Otto
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2002
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122488/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11880649/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.052430399
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