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Role of Nucleotide Binding and GTPase Domain Dimerization in Dynamin-like Myxovirus Resistance Protein A for GTPase Activation and Antiviral Activity

Myxovirus resistance (Mx) GTPases are induced by interferon and inhibit multiple viruses, including influenza and human immunodeficiency viruses. They have the characteristic domain architecture of dynamin-related proteins with an N-terminal GTPase (G) domain, a bundle signaling element, and a C-ter...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Dick, Alexej, Graf, Laura, Olal, Daniel, von der Malsburg, Alexander, Gao, Song, Kochs, Georg, Daumke, Oliver
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432294/
https://ncbi.nlm.nih.gov/pubmed/25829498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.650325
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