Modulation of fibroblast growth factor-2 receptor binding, dimerization, signaling, and angiogenic activity by a synthetic heparin-mimicking polyanionic compound.

Eitemau Tebyg

• Inhibition of anastomotic intimal hyperplasia by a synthetic nonsulphated heparin-mimicking compound
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  Cyhoeddwyd: (2002)
• A heparin-binding angiogenic protein--basic fibroblast growth factor--is stored within basement membrane.
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• Preferential self-association of basic fibroblast growth factor is stabilized by heparin during receptor dimerization and activation.
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  Cyhoeddwyd: (1996)
• Electrostatic forces as dominant interactions between proteins and polyanions: an ESI-MS study of fibroblast growth factor binding to heparin oligomers
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  Cyhoeddwyd: (2017)
• Parathyroid hormone is a heparin/polyanion binding protein: Binding energetics and structure modification
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