Modulation of fibroblast growth factor-2 receptor binding, dimerization, signaling, and angiogenic activity by a synthetic heparin-mimicking polyanionic compound.

Heparan sulfate (HS) proteoglycans play a key role in cell proliferation induced by basic fibroblast growth factor (FGF-2) and other heparin-binding growth factors. To modulate the involvement of HS, we have used a synthetic, nonsulfated polyanionic aromatic compound (RG-13577) that mimics functiona...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Miao, H Q, Ornitz, D M, Aingorn, E, Ben-Sasson, S A, Vlodavsky, I
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1997
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC507976/
https://ncbi.nlm.nih.gov/pubmed/9120000
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