Metastatic risk and resistance to BRAF inhibitors in melanoma defined by selective allelic loss of ATG5

Melanoma is a paradigm of aggressive tumors with a complex and heterogeneous genetic background. Still, melanoma cells frequently retain developmental traits that trace back to lineage specification programs. In particular, lysosome-associated vesicular trafficking is emerging as a melanoma-enriched...

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Vydáno v:Autophagy
Hlavní autoři: García-Fernández, María, Karras, Panagiotis, Checinska, Agnieszka, Cañón, Estela, Calvo, Guadalupe T., Gómez-López, Gonzalo, Cifdaloz, Metehan, Colmenar, Angel, Espinosa-Hevia, Luis, Olmeda, David, Soengas, María S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
Basic Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079679/
https://ncbi.nlm.nih.gov/pubmed/27464255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1199301
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