Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers

Nuclear 3'-end-polyadenylation is essential for the transport, stability and translation of virtually all eukaryotic mRNAs. Poly(A) tail extension can also occur in the cytoplasm, but the transcripts involved are incompletely understood, particularly in cancer. Here we identify a lineage-specif...

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Publicado no:Nat Commun
Main Authors: Pérez-Guijarro, Eva, Karras, Panagiotis, Cifdaloz, Metehan, Martínez-Herranz, Raúl, Cañón, Estela, Graña, Osvaldo, Horcajada-Reales, Celia, Alonso-Curbelo, Direna, Calvo, Tonantzin G., Gómez-López, Gonzalo, Bellora, Nicolas, Riveiro-Falkenbach, Erica, Ortiz-Romero, Pablo L., Rodríguez-Peralto, José L., Maestre, Lorena, Roncador, Giovanna, de Agustín Asensio, Juan C., Goding, Colin R., Eyras, Eduardo, Megías, Diego, Méndez, Raúl, Soengas, María S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120223/
https://ncbi.nlm.nih.gov/pubmed/27857118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13418
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