Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1

Melanomas are well-known for their altered mRNA expression profiles. Yet, the specific contribution of mRNA binding proteins (mRBPs) to melanoma development remains unclear. Here we identify a cluster of melanoma-enriched genes under the control of CUGBP Elav-like family member 1 (CELF1). CELF1 was...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Cifdaloz, Metehan, Osterloh, Lisa, Graña, Osvaldo, Riveiro-Falkenbach, Erica, Ximénez-Embún, Pilar, Muñoz, Javier, Tejedo, Cristina, Calvo, Tonantzin G., Karras, Panagiotis, Olmeda, David, Miñana, Belén, Gómez-López, Gonzalo, Cañon, Estela, Eyras, Eduardo, Guo, Haihong, Kappes, Ferdinand, Ortiz-Romero, Pablo L., Rodríguez-Peralto, Jose L., Megías, Diego, Valcárcel, Juan, Soengas, María S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740069/
https://ncbi.nlm.nih.gov/pubmed/29269732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02353-y
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