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E2F1-Dependent Oncogenic Addiction of Melanoma Cells to MDM2

One of the defining features of aggressive melanomas is their complexity. Hundreds of mutations and an ever increasing list of changes in the transcriptome and proteome distinguish normal from malignant melanocytic cells. Yet, despite this altered genetic background, a long-known attribute of melano...

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Détails bibliographiques
Auteurs principaux: Verhaegen, Monique, Checinska, Agnieszka, Riblett, Mary Beth, Wang, Shaomeng, Soengas, María S.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193861/
https://ncbi.nlm.nih.gov/pubmed/21743494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.277
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