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Red blood cell thickness is evolutionarily constrained by slow, hemoglobin-restricted diffusion in cytoplasm

During capillary transit, red blood cells (RBCs) must exchange large quantities of CO(2) and O(2) in typically less than one second, but the degree to which this is rate-limited by diffusion through cytoplasm is not known. Gas diffusivity is intuitively assumed to be fast and this would imply that t...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Richardson, Sarah L., Swietach, Pawel
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078773/
https://ncbi.nlm.nih.gov/pubmed/27777410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36018
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