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Red blood cell thickness is evolutionarily constrained by slow, hemoglobin-restricted diffusion in cytoplasm

During capillary transit, red blood cells (RBCs) must exchange large quantities of CO(2) and O(2) in typically less than one second, but the degree to which this is rate-limited by diffusion through cytoplasm is not known. Gas diffusivity is intuitively assumed to be fast and this would imply that t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Richardson, Sarah L., Swietach, Pawel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078773/
https://ncbi.nlm.nih.gov/pubmed/27777410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36018
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