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Intracellular tortuosity underlies slow cAMP diffusion in adult ventricular myocytes
AIMS: 3′,5′-Cyclic adenosine monophosphate (cAMP) signals in the heart are often confined to concentration microdomains shaped by cAMP diffusion and enzymatic degradation. While the importance of phosphodiesterases (degradative enzymes) in sculpting cAMP microdomains is well established in cardiomyo...
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| Publicado no: | Cardiovasc Res |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872880/ https://ncbi.nlm.nih.gov/pubmed/27089919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvw080 |
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