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Intracellular tortuosity underlies slow cAMP diffusion in adult ventricular myocytes
AIMS: 3′,5′-Cyclic adenosine monophosphate (cAMP) signals in the heart are often confined to concentration microdomains shaped by cAMP diffusion and enzymatic degradation. While the importance of phosphodiesterases (degradative enzymes) in sculpting cAMP microdomains is well established in cardiomyo...
में बचाया:
में प्रकाशित: | Cardiovasc Res |
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मुख्य लेखकों: | , , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Oxford University Press
2016
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872880/ https://ncbi.nlm.nih.gov/pubmed/27089919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvw080 |
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