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Intracellular tortuosity underlies slow cAMP diffusion in adult ventricular myocytes

AIMS: 3′,5′-Cyclic adenosine monophosphate (cAMP) signals in the heart are often confined to concentration microdomains shaped by cAMP diffusion and enzymatic degradation. While the importance of phosphodiesterases (degradative enzymes) in sculpting cAMP microdomains is well established in cardiomyo...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cardiovasc Res
मुख्य लेखकों: Richards, Mark, Lomas, Oliver, Jalink, Kees, Ford, Kerrie L., Vaughan-Jones, Richard D., Lefkimmiatis, Konstantinos, Swietach, Pawel
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872880/
https://ncbi.nlm.nih.gov/pubmed/27089919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvw080
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