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Single-cell O(2) exchange imaging shows that cytoplasmic diffusion is a dominant barrier to efficient gas transport in red blood cells

Disorders of oxygen transport are commonly attributed to inadequate carrying capacity (anemia) but may also relate to inefficient gas exchange by red blood cells (RBCs), a process that is poorly characterized yet assumed to be rapid. Without direct measurements of gas exchange at the single-cell lev...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Richardson, Sarah L., Hulikova, Alzbeta, Proven, Melanie, Hipkiss, Ria, Akanni, Magbor, Roy, Noémi B. A., Swietach, Pawel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7211990/
https://ncbi.nlm.nih.gov/pubmed/32321831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1916641117
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